Interleukin-2 (IL-2) is recognized as a crucial cytokine for the proliferation, survival, and expression of effector functions in activated T and NK cells. However, IL-2 is involved not only in promoting effector T and NK ...

This thesis presents worksheets for the teaching of the evolution of ecosystems on Earth. A total of seven worksheets cover the evolution from the Precambrian to the end of the Mesozoic Era, while introducing selected ...

Introduction: Orofacial clefts are one of the most common congenital craniofacial defects associated with serious health complications. The aim of any surgical intervention is to minimize these health problems in order to ...

Antibiotic resistance currently represents one of the most serious health threats. Infections caused by resistant bacteria have higher mortality rates, particularly among critically ill patients, prolong hospitalization ...

This dissertation consists of three scientific articles, two of which have already been published, and the third is currently undergoing peer review. The complete texts of the publications are appended to this thesis. This ...

The ARP2/3 complex is a heteroheptameric protein complex conserved across eukaryotes. Its role is the polymerization of actin filaments from monomeric actin. In amoebae and animal cells, the ARP2/3 complex is crucial for ...

Trichobilharzia regenti is an avian schistosome extraordinary for its neurotropism. Besides infecting its final hosts, waterfowl, it can also infect mammals where the immune response quickly kills the parasite. Yet, the ...

(EN) The first part of this dissertation thesis investigates the possibilities of analysis and characterization of liposomes using capillary electrophoresis. Our primary objectives were to identify suitable background ...

With the ever-advancing technological progress and the development of modern society, the requirement to ensure sufficient amount of quality and safe food, water resources and the overall safety of the environment in which ...

Cytokinins are adenine derivatives and a group of plant hormones that regulate many physiological processes, including cell division, root and shoot growth, and senescence delay. Cytokinins transported via xylem have a ...

Manifestations of social disparities take different forms and have various causes. In extreme cases, they lead to social exclusion. On the one hand, transport is an instrument for excluded individuals to participate in ...

Biological processes are often associated with the structure and dynamics of biomacromolecules. One of the main biomacromolecules are proteins, whose structure and dynamics are complex and require special approaches. The ...

Microinvertebrate consumers are important players in carbon and nitrogen cycling on glacier surfaces (the supraglacial). They constitute the highest level of the supraglacial trophic network, and their grazing significantly ...

Individualita v hlasových projevech je zásadní pro komunikaci zvířat a usnadňuje rozpoznávání jedinců v rámci různých taxonů i sociálních kontextů. Tato disertační práce se zaměřuje na dva sesterské druhy pěvců, lindušku ...

The dissertation deals with the long-term impacts of new road infrastructure in Czechia put into operation between 2005 and 2015. The object of the research is to find a link between the development of key socio-economic ...

Univerzita Karlova Přírodovědecká fakulta Studijní program: Regionální a politická geografie Mgr. Martin Kebza METROPOLIZAČNÍ PROCESY V ČESKU A POLSKU: REGIONÁLNĚ - GEOGRAFICKÁ KOMPARATIVNÍ ANALÝZA METROPOLITANIZATION ...

This thesis explores the gravity and magnetic aspects (functionals) derived from the gravity gradient tensor (GGT) and magnetic gradient tensor (MGT). These functionals include topography, gravity disturbance, GGT components, ...

This doctoral thesis focuses on the design, synthesis, and characterization of novel polymer materials responsive to physical and chemical stimuli. The presented findings will serve mainly for improving polymer-based ...

The bacterium Staphylococcus aureus is currently one of the most frequently detected pathogenic bacteria in laboratory practice. It is particularly problematic when it comes to antimicrobial resistance. An important tool ...

The work is focused on creating new teaching materials to support the teaching topics of nucleic acids in secondary schools, specifically in high schools. The theoretical part of the work contains an analysis of the topic ...

Sense of place and place attachment are topics that resonate within the discourse of subject didactics, including geography education, and is also reflected in the new Framework Educational Program for Basic Education. ...

The aim of this Master's Thesis was to create high school education materials on the topic of luminescence using the inquiry-based science education, which will be accessible to both students and teachers. The lesson is ...

A world without chemicals is unimaginable, yet many of us perceive them negatively. This bachelor's thesis focuses on chemophobia, the unfounded fear of chemicals and chemistry as such, its possible causes, and the groups ...

This diploma thesis deals with the initial knowledge of 7th-grade pupils of four selected elementary schools in the Czechia, namely the knowledge of the regional geography of Europe. The thesis consists of two main parts ...

Shrnutí Tato práce se zabývá syntézou a charakterizací vysokoteplotních a nízkoteplotních mag- netoelektrických nanočástic, které mají ferimagnetické jádro CoFe2O4 a feroelektrický plášť BaTiO3 (vysokoteplotní) nebo NiFe2O4 ...

The anaerobic protist Giardia intestinalis is the most common intestinal parasite of human. Parasitic life style and evolutionary divergence have led to remarkable adaptations of cellular compartments and metabolic pathways ...

Parasites of the genus Lankesterella are blood coccidia described in various passerine species and represent a less explored group within the phylum Apicomplexa. This study examined the prevalence and persistence of this ...

Cognitive performance in older adults from European countries: An epidemiological analysis of Wave 9 SHARE data Abstract: The aging of the European population is a current topic, and it is associated with the issue of ...

The aim of this thesis is to compare meanings and interpretations of selected key Holocaust memory sites in Czechia and Germany, and their role in culture of remembrance and collective memory. The chosen memory sites are ...

Copper ions are, along with iron and zinc, one of the most commonly occurring metal ions in biological systems. Their electronic structure - especially when it comes to (coupled) polynuclear Cu centers in metalloproteins ...

The thesis deals with the remains of silver mining in the Tábor region. The introductory theoretical part is based on the content analysis of domestic and foreign literary sources and map documents, summarizing general ...

The topic of genetics has long been evaluated as one of the most challenging topics in the teaching of biology. The individual concepts of genetics are often very abstract and difficult to grasp, which leads to the creation ...

With a worldwide distribution and diversification into almost 400 species, Viperidae is considered one of the evolutionarily most successful families of snakes. The group is of broad scientific and public interest for its ...

Interleukin-2 (IL-2) is recognized as a crucial cytokine for the proliferation, survival, and expression of effector functions in activated T and NK cells. However, IL-2 is involved not only in promoting effector T and NK ...

Drought is currently one of the most significant stress factors affecting agricultural production worldwide. For this reason, various methods are being investigated to mitigate the effects of this stressor on plants. One ...

A conceptual framework, along with its accompanying conceptual inventory, represents a cornerstone for effective teaching at all levels of education. In the continually evolving field of neurobiology, their significance ...

For most primary and secondary schools in the Czech Republic, outdoor education, despite its long-emphasized benefits, presents a challenge in overcoming various organizational, safety, and methodological obstacles, making ...

This work deals with the automated creation of tessellation-based planar cartographic cartogram, otherwise known as mosaic cartogram. Its principle is based on geometric transformation of the mapped area according to ...

This thesis examines destination management and the possibilities for further development of tourism in the Kutnohorsko Kolínsko destination. The main goal is to analyze the current state of tourism in this area and propose ...

The thesis focuses on the topic of metropolitan cooperation in the Brno Metropolitan Area. It is a contribution to the current scholarly debate on metropolitan governance, especially to its branch focusing on low-institutionalised ...