Přírodovědecká fakulta
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GEOBIBLINE - plné texty [10555]
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Habilitační práce [85]
Habilitations -
Kvalifikační práce [21581]
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Kvalifikační práce obhajované před rokem 2006 [0]
Theses defended before year 2006
Poslední příspěvky
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Characterization of novel cysteine proteases and their inhibitors in blood-feeding ticks and allergenic mites
Výsledek obhajoby: UZNÁNO(Univerzita Karlova, Přírodovědecká fakulta, 2026)Datum obhajoby: 6. 2. 2026Proteolytic systems play a crucial role in medically relevant arthropods in processes such as host-parasite interactions and the development of allergic hypersensitivity. This dissertation focuses on cathepsin proteases ... -
Morphology and surface modification of boron-doped diamond electrodes in relation to electrochemical properties and interactions with organic compounds
Výsledek obhajoby: UZNÁNO(Univerzita Karlova, Přírodovědecká fakulta, 2026)Datum obhajoby: 4. 2. 2026Boron doped diamond is nowadays a frequently used electrode material, however, the heterogeneity of its surface still raises questions on the interplay between the material, its surface composition and morphology, and its ... -
The role of respiration in tumour growth
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2026)Datum obhajoby: 4. 2. 2026Cancer cells lacking mitochondrial DNA (mtDNA) require horizontal mitochondrial transfer (HMT) to restore the respiratory function. Beyond its canonical role in ATP production, mitochondrial respiration is essential for ... -
Diverzita vrubounovitých brouků (Coleoptera: Scarabaeoidea) v raném fosilním záznamu
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2026)Datum obhajoby: 4. 2. 2026The study provides an attempt to summarize current knowledge about the fossil record of the Scarabaeoidea. It includes an up-to-date annotated list of all formally described fossil taxa of the superfamily Scarabaeoidea, ... -
The resource competition between honeybees (Apis mellifera) and wild bees (Hymenoptera: Apoidea) in anthropogenic landscapes
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2026)Datum obhajoby: 4. 2. 2026Pollination by wild bees provide essential ecosystem services and support plant reproduction in agricultural and urban landscapes. However, populations of wild bees are declining due to multiple stressors, including ... -
Efekt slabé kontaminace kadmiem na zdravotní stav a kondici u zebřičky pestré
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2026)Datum obhajoby: 4. 2. 2026Heavy metals are important contaminants of the environment, that are released mainly as a result of industrial activities. Cadmium is a toxic heavy metal, which is accumulated by organisms and is linked with negative effects ... -
Vztah mezi fyzickou zdatností a atraktivitou u žen
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2026)Datum obhajoby: 3. 2. 2026Attractiveness is a significant factor influencing human preferences in mate choice. From the perspective of evolutionary psychology, it is assumed that traits perceived as attractive refer to the biological quality of an ... -
Host-pathogen interactions during in vitro hepatitis B virus infection
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2026)Datum obhajoby: 3. 2. 2026Hepatitis B virus (HBV) is a human pathogen that causes acute and chronic liver disease. While vaccination effectively prevents new infections, current antiviral therapies rarely eliminate HBV in chronically infected ... -
Vznik a přetrvávání barevného polymorfismu u krysy obecné
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2026)Datum obhajoby: 3. 2. 2026Color polymorphism describes the variability in coloration of individuals within a species. A striking form of it is variability caused by the presence of a subset of melanistic individuals within populations. This phenomenon ... -
Evoluční a demografická historie arabských chameleonů
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2026)Datum obhajoby: 3. 2. 2026In terms of chameleon biogeography, only the genus Chamaeleo occurs on the Arabian Peninsula, represented by three species: C. calyptratus, C. arabicus, and C. chamaeleon. Chamaeleo chamaeleon has the largest range, extending ... -
Identifikace inhibitorů polymerázové domény proteinu NS5 viru dengue
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2026)Datum obhajoby: 3. 2. 2026Flaviviruses represent an important group of RNA viruses that include several human pathogens, among which dengue virus is one of the most significant. Dengue virus infection affects tens of millions of people worldwide ... -
Neofobie a podmíněná chuťová averze u krys
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2026)Datum obhajoby: 3. 2. 2026Neophobia and conditioned taste aversion are key behavioral mechanisms that enable wild populations of rats to respond effectively to potential food risks in their environment. The aim of this thesis was to experimentally ... -
Modulation of the heat shock protein 90 (HSP90) by reversible acetylation
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2026)Datum obhajoby: 3. 2. 2026HSP90α is an ATP-dependent chaperone whose activity, among other things, is modulated by lysine acetylation, but the functional impact of individual acetylation sites remains unclear. This thesis examines how acetylation ... -
Příprava myších modelů pro výzkum nádorové biologie primárních hematologických malignit.
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2026)Datum obhajoby: 3. 2. 2026Acute myeloid leukemia (AML), myelodysplastic syndrome (MDS) and multiple myeloma (MM) areheterogeneous malignant hematological diseases that arise as a result of disorders of hematopoieticstem or precursor cells of the ... -
Interactions of Hepatitis B virus proteins with the host cell
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2026)Datum obhajoby: 3. 2. 2026Hepatitis B virus (HBV) remains a major global health threat, with over 250 million people infected and causing more than a million deaths annually. In hepatocyte nuclei, the host's Smc5/6 complex acts as a restriction ... -
Development and evaluation of a new molecular tool for Entamoeba histolytica.
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2026)Datum obhajoby: 3. 2. 2026Entamoeba histolytica, the causative agent of amoebiasis, remains challenging to manipulate genetically, and existing tools rarely permit coordinated expression of two genes. This thesis introduces DualP, a modular episomal ... -
Staré a nové hrozby: subjektívne emocionálne hodnotenie
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2026)Datum obhajoby: 3. 2. 2026Emotions such as fear, disgust, and anger are key adaptive mechanisms whose function has been shaped by evolution. However, the modern environment brings new types of threats that differ significantly from evolutionarily ... -
Mikroprostředí mezenchymálních kmenových buněk v interakci s leukemickými buňkami in vitro
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2026)Datum obhajoby: 3. 2. 2026Establishing reliable in vitro models of the leukemic microenvironment fundamentally depends on the selection of an adherent cell population capable of mimicking the functions of the bone marrow stromal niche. However, ... -
Cellular and Humoral Immune Responses against Viral Infections
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2026)Datum obhajoby: 3. 2. 2026The adaptive immune system represents a key component of the host defense against viruses causing both acute and persistent infections. This thesis deals with two viral pathogens: Severe Acute Respiratory Syndrome Coronavirus ... -
Ochranárska genetika peripatrických populácií losa v strednej Európe
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2026)Datum obhajoby: 3. 2. 2026The Eurasian elk (Alces alces) is a native species of large ungulate in Europe that underwent a significant bottleneck effect in modern history. However, partly due to suitable management, the species gradually expanded ...
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