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Zobrazují se záznamy 131-140 z 20864
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Využitie voltampérometrie a ampérometrie pri stanovení warfarínu
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2025)Datum obhajoby: 3. 6. 20255 Abstract This thesis deals with the study of the electrochemical behaviour of the anticoagulant drug warfarin (WAR). A screen-printed carbon electrode (SPCE) and an ultra-trace graphite electrode (UTGE) were used as ... -
Exprese a charakterizace nové fungální chitindeacetylasy
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2025)Datum obhajoby: 4. 6. 2025Chitin is the second most abundant biopolymer in nature. Its derivatives chitosan and especially chitooligosaccharides exhibit a broad spectrum of biological activities with applications in biomedicine, agriculture, food ... -
Evoluční dynamika karyotypové diferenciace sekáčů (Arachnida: Opiliones).
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2025)Datum obhajoby: 9. 6. 2025The order of harvestmen (Opiliones) represents one of the oldest lineages of arachnids, with occurrences documented as far back as the Devonian period. Despite their long evolutionary history and the colonization of a wide ... -
Leaf anatomical and physiological adaptations in extreme conditions of the Western Himalayas
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2025)Datum obhajoby: 6. 6. 2025High-mountain plants had to develop various adaptations to survive in harsh conditions. While plant ecologists have been focusing on mountain regions for a long time, there is still not much known about adaptations of ... -
Fyziologický stav rostlin zelených zdí a fasád v závislosti na mikroklimatu stanoviště
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2025)Datum obhajoby: 6. 6. 2025With advancing climate change, more extreme weather events and increasing urbanization, the conditions of the cities are worsening and also the space for green areas is decreasing. Higher temperatures and heat waves continue ... -
Modeling spatio-temporal dynamics in primary visual cortex using deep neural network model
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2025)Datum obhajoby: 6. 6. 2025Recent advances in computational neuroscience and machine learning have enabled increasingly sophisticated models of neuronal systems. How- ever, standard deep neural networks (DNNs) often prioritize task perfor- mance ... -
Physics-based protonation of protein-ligand complexes
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2025)Datum obhajoby: 6. 6. 2025Title: Physics-based protonation of protein-ligand complexes Author: Bc. Miloš Halda Supervisor: RNDr. Martin Lepšík, Ph.D. Consultant: doc. RNDr. Jan Řezáč, Ph. D. Abstract: Structure-based computer-aided drug design ... -
Sources of improvement in multiple sclerosis prognosis in the last 30 years
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2025)Datum obhajoby: 6. 6. 2025Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease that damages the central nervous system (CNS). Although its exact cause remains unknown, multiple factors are thought to contribute to its pathogen- esis. ... -
Predicting Protein Thermostability With a Focus on Antibodies
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2025)Datum obhajoby: 6. 6. 2025Thermostability is key to successful protein engineering and therapeutic antibody development; accurate prediction accelerates the identification of stable proteins and the design of robust variants. This thesis evaluates ... -
Vývojová dynamika konkurenceschopnosti evropských regionů mezi lety 2016 a 2022
Výsledek obhajoby: OBHÁJENO(Univerzita Karlova, Přírodovědecká fakulta, 2025)Datum obhajoby: 6. 6. 2025The topic of this thesis is the development of the competitiveness of European NUTS 2 regions for the period 2016 to 2022, which is examined on the basis of EU Regional Competitiveness Index values. The aim is to reveal ...