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Postoj pacientů dlouhodobě sledovaných pro dg. Maligní melanom k prevenci a dispenzarizaci
Defence status: DEFENDED(Univerzita Karlova, 2. lékařská fakulta, 2013)Date of defense: 24. 10. 2013Souhrn v anglickém jazyce Malignant melanoma is the most lethal skin cancer whose incidence has been worldwide increasing. The prognosis of the disease is dependent on many factors - the effected locality, age, form of the ... -
Diagnostika virových gastoenteritid u dětí do pěti let metodou elektronové mikroskopie.
Defence status: DEFENDED(Univerzita Karlova, 2. lékařská fakulta, 2013)Date of defense: 8. 7. 2013Acute gastroenteritis is one of the most frequent diseases in children worldwide and remains the main cause of childhood morbidity and mortality, particularly in developing countries. Each year as many as 1.5 million ... -
Využití biologické zpětné vazby v rehabilitaci pacientů s poruchou posturální stability
Defence status: DEFENDED(Univerzita Karlova, 2. lékařská fakulta, 2013)Date of defense: 20. 5. 2013This dissertation is providing evidence that rehabilitation with biofeedback improves postural stability in patients with poor balance. We used two methods of biofeedback during the rehabilitation of the patient groups, ... -
Studium fluorescenčních produktů v mitochondriích po napadení volnými radikály
Defence status: DEFENDED(Univerzita Karlova, 2. lékařská fakulta, 2013)Date of defense: 21. 3. 2013Lipofuscin-like pigments are products of reactions involving free radical attack onto molecules with nucleophilic groups. They can be for med, for example, in the reactions between lipid peroxidation decomposition products, ... -
Studium faktorů ovlivňující vazebnou specifitu 14-3-3 proteinů.
Defence status: DEFENDED(Univerzita Karlova, 2. lékařská fakulta, 2013)Date of defense: 24. 10. 2013The 14-3-3 proteins are dimeric molecules with a characteristic shape and molecular mass about 30 kDa found in all eukaryotes. They are playing a key role in a variety of biological processes such as signal transduction, ... -
Poruchy regulace imunity - alergie a autoimunitní onemocnění
Defence status: DEFENDED(Univerzita Karlova, 2. lékařská fakulta, 2013)Date of defense: 16. 9. 2013The pathology of immune system can lead to immune disorders. Immunodeficencies are caused by insufficient or missing immune response. On the other hand, allergies and autoimmune disorders represent a consequence of wrong ... -
Vliv velikosti defektu a operační techniky na dlouhodobou morbiditu dětí s vrozenou brániční kýlou
Defence status: DEFENDED(Univerzita Karlova, 2. lékařská fakulta, 2013)Date of defense: 16. 9. 2013The influence of defect size and surgical technique on the long-term morbidity of children with congenital diaphragmatic hernia Objective: The aim of this study is to evaluate the effects of diaphragm reconstruction using ... -
Prognóza akutní lymfoblastické leukémie u dětí v závislosti na nových klinicko-biologických faktorech
Defence status: DEFENDED(Univerzita Karlova, 2. lékařská fakulta, 2013)Date of defense: 30. 1. 2013Great progress has been achieved in the diagnostics and therapy of childhood acute lymphoblastic leukemia (ALL) during the last few decades and the permanent cure rate for children and adolescents has risen to nearly 90%. ... -
Mechanisms of insulin resistance and β - cell failure in type 2 diabetes. Effective diet against o minous octet
Defence status: DEFENDED(Univerzita Karlova, 2. lékařská fakulta, 2013)Date of defense: 17. 1. 2013Background and Aims: Dietary intervention is one of the key components in type 2 diabetes (T2D) management. Vegetarian diet is a promising alternative in the nutritional treatment of T2D. The aims of our study were: 1. To ... -
Patofyziologické mechanismy a optimalizace diagnostiky vrozené adrenální hyperplazie
Defence status: DEFENDED(Univerzita Karlova, 2. lékařská fakulta, 2013)Date of defense: 13. 6. 2013Autoreferát Summary Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive diseases which are characterized by inadequate secretion of steroid hormones of the adrenal cortex. The most common type of CAH is ...